CAS Number
77591-33-4
Other Names
TRIFLUOROMAGNESATE, MGF, Mechano Growth Factor
IUPAC Name
N/A
Molecular Formula
C₁₂₁H₂₀₀N₄₂O₃₉
Molecular Weight
2888.16
Purity
≥99% Pure (LC-MS)
Liquid Availability
N/A
Powder Availability
2 milligrams (lyophilized/freeze-dried)
Storage Condition
Store cold, keep refrigerated. Do NOT freeze.
Terms
All products are for laboratory developmental research USE ONLY. Products are not for human consumption.
 
 
What is Mechano Growth Factor
Mechano Growth Factor (MGF) is a peptide commonly found in skeletal muscle and helps respond to muscle stress and injury by regulating cell proliferation. MGF is considered to be a variant splice of insulin-growth factor 1 (IGF-1). IGF-1 is unique as it is composed out of 6 exons and 5 mRNA codings for different isoforms. These isoforms, IGF-1Ea, IGF-1Eb, and IGF-1Ec, were found through mRNA splicing. IGF-1Ea is the isoform normally found in the liver, while IGF-1Eb and IGF-1Ec are found in the muscle. Animal studies have found that when muscle tissue is damaged by stress or injury, the expression of IGF-1Eb is upregulated. Since the damage to the muscle was caused in a “mechano-sensitive manner”, the isoform was given the common name, Mechano Growth Factor.