| CAS Number | 77591-33-4 |
| Other Names | TRIFLUOROMAGNESATE, MGF, Mechano Growth Factor |
| IUPAC Name | N/A |
| Molecular Formula | C₁₂₁H₂₀₀N₄₂O₃₉ |
| Molecular Weight | 2888.16 |
| Purity | ≥99% Pure (LC-MS) |
| Liquid Availability | N/A |
| Powder Availability | 2 milligrams (lyophilized/freeze-dried) |
| Storage Condition | Store cold, keep refrigerated. Do NOT freeze. |
| Terms | All products are for laboratory developmental research USE ONLY. Products are not for human consumption. |
What is Mechano Growth Factor
Mechano Growth Factor (MGF) is a peptide commonly found in skeletal muscle and helps respond to muscle stress and injury by regulating cell proliferation. MGF is considered to be a variant splice of insulin-growth factor 1 (IGF-1). IGF-1 is unique as it is composed out of 6 exons and 5 mRNA codings for different isoforms. These isoforms, IGF-1Ea, IGF-1Eb, and IGF-1Ec, were found through mRNA splicing. IGF-1Ea is the isoform normally found in the liver, while IGF-1Eb and IGF-1Ec are found in the muscle. Animal studies have found that when muscle tissue is damaged by stress or injury, the expression of IGF-1Eb is upregulated. Since the damage to the muscle was caused in a “mechano-sensitive manner”, the isoform was given the common name, Mechano Growth Factor.